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Cluster Randomized Clinical Trial Suggests Effectiveness of Systematic Echocardiographic Screening of Children for Latent Rheumatic Heart Disease

Results of the NEPAL II trial presented in the Late Breaking Clinical Science Session at the American Heart Association’s Scientific Sessions 2019 in Philadelphia, and published in JAMA Cardiology.

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Rheumatic Heart Disease

Rheumatic fever results from an autoimmune response to a streptococcal throat infection and may lead to rheumatic heart disease.

Aims

Early detection of clinically silent valvular heart disease and timely implementation of secondary antibiotic prevention may prevent progression of disease.

Program

We perform active surveillance for rheumatic heart disease by echocardiographic screening in regions where rheumatic heart disease is endemic.

Epidemiology

Rheumatic heart disease continues to be a major health care challenge in low and middle income countries where it affects up to 5% of children and adolescents.

Research

We conduct independent population-based surveys of rheumatic heart disease and longitudinal cohort studies.

Documentary Nepal

The documentary movie provides a summary of the active surveillance program for rheumatic heart disease in Nepal.
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    Nepal

    The Sunsari district is situated on the foothills of the Lower Himalayan Range in Eastern Nepal.

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    Switzerland

    Bern University Hospital is one of five academic teaching hospitals in Switzerland and home to the Swiss Cardiovascular Center.

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    Peru

    The Arequipa metropolitan area is located in the southern part of Peru at an altitude of more than 2300 meters above see level.

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    American Samoa

    American Samoa consists of five main islands and is located in the South Pacifc Ocean.

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RHeaDY

Rheumatic Heart Disease in the Young (RHeaDY) is a nonprofit organization committed to the control of rheumatic heart disease low- and middle income countries. www.rheady.org
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  • Home
  • Rheumatic Heart Disease
    • About the disease
    • Epidemiology
  • Program
    • Aims
    • Our values
    • NEPAL I
    • NEPAL II
    • NEPAL III
    • NEPAL IV
  • Commitment
    • RHeaDY
    • SUMMIT
  • Research
    • Peer-reviewed publications
    • Podcasts
    • Documentary
    • Data sharing
  • Get involved

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