The NEPAL II study was a cluster randomized clinical trial to investigate the effectiveness of systematic echocardiographic screening in combination with secondary antibiotic prophylaxis on the prevalence of rheumatic heart disease.


B.P. Koirala Institute of Health Sciences, Dharan, Nepal
Bern University Hospital, Bern, Switzerland
Applied Health Research Centre, Li Ka Shing Knowledge Institute of St Michael's Hospital, Department of Medicine and Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada